Job Abstract

Under supervision of the Principal Investigator and the Postdoctoral Scholar, the Staff Research Associate (SRA) will provide basic technical support in the research laboratory modeling the molecular and genetic basis of frontotemporal dementia and testing therapeutic treatments. This includes benchwork involving molecular and cellular biology techniques. The majority of work will be performing mammalian tissue culture (generating stable cell lines as well as primary neuronal cultures; cell culture maintenance), RNA and protein extraction and analysis (RT-PCR and Western blotting, respectively), as well as investigating cytotoxicity and therapeutic effects of candidate compounds in vitro and in vivo (mouse). The SRA will be involved in generating DNA plasmids for cell culture studies; performing PCR and gel electrophoresis; immunocytochemistry and immunohistochemistry; preparing buffers, solutions, and chemicals for lab experiments; basic data analysis and interpretation; maintaining database of experimental results; assisting with figures for grant applications and publications; providing technical assistance in the lab, including assisting other members of the lab; and assisting with training of lab assistants and students.

Salary Range: $25.75 - $30.71 Hourly

Required:

General working knowledge of molecular biology, molecular genetics, cell biology, human
genetics, animal husbandry (mouse) and/or neuroscience theories and principles.

Knowledge of standard laboratory equipment and supplies.

Good communication skills and ability to work well with multiple individuals.

Ability to maintain an organized working area.

Ability to keep accurate and organized lab records.

Ability to work on several projects simultaneously and to switch focus as needed.

Knowledge of chemistry to prepare solutions for lab experiments.

Knowledge of laboratory safety procedures for handling chemical, biohazard, and medical
waste.

Knowledge of basic molecular biology/cell biology/genetic techniques.

Working knowledge and ability in the use of computers (PC and MAC operating systems).

Skill in using various computer software (e.g., Microsoft Office, Adobe products, etc.)

Excellent attention to detail, for accurate data entry and analysis.

Good organization and time management skills. Always punctual.

Ability to learn new laboratory techniques and new lab equipment, as needed.

General knowledge of University procedures and compliance with Environmental Health and Safety guidelines.