Job Abstract

HOW MIGHT YOU DEFY IMAGINATION?

If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.

Scientific Associate Director - Computational Medicinal Chemistry

What you will do

Let’s do this. Let’s change the world. Amgen is seeking an experienced and accomplished Computational Medicinal Chemist to join our drug discovery efforts in the Computational Chemistry group, which is part of the broader Computational and Data Sciences team at Amgen Research. This position is a senior scientific role with significant leadership responsibilities and opportunities.

• Participate on multiple interdisciplinary project teams and play a key role in defining project strategy and achieving project milestones
• Apply structure-based, ligand-based and machine learning/generative AI design to advance drug discovery projects
• Coordinate collaborations with external partners by joining joint team meetings, enabling seamless data transfer and platform deployment
• Deploy a retrosynthetic platform to maximize chemical tractability of designed molecules. Work cross-functional to prioritize and coordinate compound synthesis at CROs and to optimize compound acquisition and internalization
• Take an active leadership role in guiding new AI/ML technology developments and new protein degradation workflows
• Contribute to guide infrastructure improvements, software portfolio recommendations and prospecting of relevant cutting-edge computational technologies/companies

The location for this position is either at our Thousand Oaks (CA) site or remote

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Ph.D. degree and 4 years of experience in computational or medicinal chemistry

Master’s degree and 7 years of experience in computational or medicinal chemistry

Bachelor’s degree and 9 years of experience in computational or medicinal chemistry

• PhD. in Computational Chemistry or Medicinal Chemistry or related field
• Proven accomplishments supporting drug design projects with 5+ years of relevant experience in the biopharmaceutical industry
• Experience leading cross-functional teams in a matrix environment
• Experience in the field of computational chemistry in an industry setting and good knowledge of related and adjacent disciplinary areas
• Experience in the field of medicinal chemistry in an industry setting with the ability to deploy a retrosynthetic platform to improve chemical tractability
• Thorough understanding of the drug discovery process from lead screening to late-stage optimization and know how to enhance the impact of computational modeling
• Good external publication record, excellent communication and organizational skills and demonstrated ability as a team leader
• Experience managing people is desirable

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans and bi-annual company-wide shutdowns
• Flexible work models, including remote work arrangements, where possible

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range