The successful candidate will work in an interdisciplinary discovery team focusing on extrahepatic targeting. She/ He will be an innovative leading scientist with the ability to work independently and collaboratively, design and carry out experiments and propose creative solutions to challenging problems. Responsibilities Design and execute in vitro and in vivo studies to facilitate drug discovery and platform development in various disease areas Develop, validate, and perform assays to characte... more details
Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI and San Diego, CA. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
The successful candidate will work in an interdisciplinary discovery team focusing on extrahepatic targeting. She/He will be an innovative leading scientist with the ability to work independently and collaboratively, design and carry out experiments and propose creative solutions to challenging problems.
Responsibilities
Design and execute in vitro and in vivo studies to facilitate drug discovery and platform development in various disease areas
Develop, validate, and perform assays to characterize ligand-receptor interactions and to gain mechanistic understanding of drug delivery
Present research findings to project teams and governance bodies and prepare study reports
Maintain a high level of productivity in the lab and perform critical experiments
Guide junior scientists on the team
Requirements
PhD in biology, bioengineering, biochemistry, or a related field with at least 5 years of relevant experience in biotech or pharmaceutical industry
Expertise in developing endpoint & kinetic assays, such as luminescence & fluorescence assays, activity assays, imaging-based assays
Strong background in characterization of ligand-receptor interactions using molecular, cellular, and biochemical approaches
Experienced in RNA isolation, real-time PCR, RNA-seq
Hands-on experience with cell culture and FACS cell sorting
Ability to adapt well to fast changing goals and research directions
Proven scientific accomplishments including publications, conference presentations or patents
Preferred
Knowledge and experience with protein sciences
Familiarity with various therapeutic areas
California pay range
$14,000—$170,000 USD
Arrowhead provides competitive salaries and an excellent benefit package.
All applicants must have authorization to work in the US for a company.
Job Abstracts is an independent Job Search Engine. Job Abstracts is not an agent or representative and is not endorsed, sponsored or affiliated with any employer. Job Abstracts uses proprietary technology to keep the availability and accuracy of its job listings and their details. All trademarks, service marks, logos, domain names, and job descriptions are the property of their respective holder. Job Abstracts does not have its members apply for a job on the jobabstracts.com website. Additionally, Job Abstracts may provide a list of third-party job listings that may not be affiliated with any employer. Please make sure you understand and agree to the website's Terms & Conditions and Privacy Policies you are applying on as they may differ from ours and are not in our control.
We would like to take a second to Welcome You to Job Abstracts, the nation’s largest Pure Job Board. With over 3.1 million job listings from 15,000+ Companies & Organizations, we help job searchers find careers that match their interests. As an anonymous user, you have probably discovered how easy our system is to use. However, you have just scratched the surface of what we can offer.
We encourage you to Register so you can use our most powerful features: searching with multiple terms, setting up multiple locations, establishing favorite companies, and accessing your search history. If you find a job you like, you can apply directly for it, and then, keep notes on it. We will also keep a lookout for jobs that match your search terms and email you when we find something you may like.
You can register for free and the system is free to use. If you like our system so far, click on Register and unlock the power required by serious job searchers.
Any time you conduct a search, the system shows you job matches, ranked by their Relevance Score (RS).
The score is calculated by a proprietary algorithm that uses Intelligent Machine Learning.
The Relevance Score tells you how well the job opportunity matches your search term or terms.
When not logged in, the system is limited to one search term. Scores for single term matches are usually lower.
When you register, log in, and set up multiple terms prioritized by importance, the jobs found for you will receive a much higher Relevance Score.