Lonza Houston is looking for a Principal Scientist who will be a process expert, able to provide in-depth technical support via multiple customer project teams to deliver the required complex technical process documentation in collaboration, negotiation and discussion with external customers as well as other internal cross functional team members providing oversight through to a robust capable cGMP scale process. He/ She will have an established internal network and have influence and credibilit... more details
Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.
Lonza Houston is looking for a Principal Scientist who will be a process expert, able to provide in-depth technical support via multiple customer project teams to deliver the required complex technical process documentation in collaboration, negotiation and discussion with external customers as well as other internal cross functional team members providing oversight through to a robust capable cGMP scale process. He/She will have an established internal network and have influence and credibility across operations in area of expertise and with MSAT team senior leadership management. In addition, he/she will act as a mentor to other MSAT team members, potentially have a junior staff reporting line, and be an SME for process operations. The Principal Scientist will act as the first point of contact for MSAT for process technical troubleshooting and scientific input within the MSAT team, internal stakeholders and Lonza’s clients
Key responsibilities:
Representative within multiple customer facing internal and external product project teams.
Use a standard methodology/procedure to successfully support transfer processes into cGMP manufacturing, from development through MSAT pilot scale facilities.
Suggest and self-govern the implementation of potential optimizations aspects within Lonza’s new product introduction strategy in alignment with Lonza’a Global MSAT CGT network.
Fully accountable for the management of technical risks associated with process transfer, identification & introduction of new raw materials for pilot and production scale batches and work cross functionally to ensure communication of all critical process and technical information such that projects meet the required deadlines/customer outcomes.
Provides technical support, process monitoring and complex data analysis.
Responsible for delivering effective operator training for critical unit/process operations and off line completion of quality actions (e.g. deviations, change controls, CAPA’s) working effectively in cross functional teams to deliver improvements to required outcomes.
Provide immediate resolution of identified manufacturing process issues through use of knowledge and experience, leading RCA procedures to ensure continuous improvements are made to the cGMP manufacturing processes and operations.
Will work with SMEs to develop knowledge base, deepen process understanding and also lead/coach junior level team members on specific technical problem resolution through sharing key knowledge.
Proactively anticipates, evaluates, and resolves technical challenges within area of expertise. Is self-managed in preventing deviations in unit operations including interaction and strong communication with both internal and external team(s) resources to achieve successful outcomes and to facilitate continual learning through experience.
Understands and looks to introduce new technologies and how they may be applicable to process innovation, cost or yield improvement.
Provide onboarding support and coach of new MSAT staff.
Point of contact for global initiatives for process/procedure improvements
Responsible for technical evaluation of manufacturing feasibility of processes from potential new customers.
Key requirements:
Minimal of a Bachelor’s Degree in Biological science or biochemical engineering disciplines
Prefer M.S or Ph.D in Biological science or biochemical engineering disciplines
10+ years experience Background in technology transfer, process development, manufacturing operations, preferably in Viral Vectors.
Able to communicate status, needs, forecasts, risks and timelines effectively to management.
Is not afraid to make decisions for the group.
Demonstrates an ability to find creative solutions to issues and obstacles
Demonstrates critical thinking skills in problem-solving and decision making;
In-depth understanding of large-scale biotechnology unit operations.
USP: Experienced in aseptic technique and mammalian cell culture, scale-up, bioreactor operations and harvest. Experience with viral-vector production is a plus.
DSP: Experienced in various chromatography, UFDF, filtration operations. Experienced with aseptic fill finish operations
People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.
Lonza is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a qualified individual with disability, protected veteran status, or any other characteristic protected by law.
