ECLIPSE (Evolution of Cancer, Leukemia and Immunity Post Stem Cell Transplant) is a novel organization within the Therapeutics Discovery platform at MD Anderson Cancer Center, Houston, Texas, with the mission of making MDACC and its partners recognized leaders in the identification and development of innovative immunooncology therapies that will cure all hematologic malignancies. We are seeking a highly motivated individual with a strong foundation in computer science concepts and an understandi... more details
ECLIPSE (Evolution of Cancer, Leukemia and Immunity Post Stem Cell Transplant) is a novel organization within the Therapeutics Discovery platform at MD Anderson Cancer Center, Houston, Texas, with the mission of making MDACC and its partners recognized leaders in the identification and development of innovative immunooncology therapies that will cure all hematologic malignancies.
We are seeking a highly motivated individual with a strong foundation in computer science concepts and an understanding of molecular / cancer biology. The Institute Associate Scientist in Computational Biology will be responsible for deploying innovative computational pipelines, algorithms and dashboard for bulk or single cell next generation DNA sequencing and proteomic data. Successful candidates will conduct data analysis of complex biological experiments and collaborate with experimental scientists to develop novel immunotherapy targets.
Education/Qualifications
* Bachelor’s degree in Bioinformatics, Computational Biology, Data Science, Biostatistics, Computer Science, Applied Mathematics or related field.
* Proficient coding in one or two computer languages, Python, R, Bash, Rust/C++ and etc.
* Experience developing large-scale data analysis pipeline in high-performance environment.
* Experience developing large-scale data visualization and management dashboard.
* Experience working on bulk or single cell NGS data, and be familiar with popular bioinformatics tools, such as samtools, bwa, GATK, minimap2, STAR, CellRanger, and Seurat.
* Demonstrated knowledge of data science and bioinformatics within a technical discipline (e.g., bioinformatics, statistics, computer science, artificial intelligence, deep learning.)
Preferred Education/Qualifications
* Master or PhD level degree.
* Practical experience in pipeline engine Snakemake, Nextflow, Cromshell or other equivalent.
* Practical experience in working in HPC, or Cloud like AWS, Azure or GCP.
* Practical experience in data visualization dashboard framework, R/Shiny, Python/Streamlit or R/Dash.
* Practical experience in statistical modeling, machine learning and deep learning using the tools or frameworks,such as TensorFlow, PyTorch, Python/statsmodels, scikit-learn, and other equivalent.
* Experience analyzing ATAC-seq data.
* An understanding of LIMS would be desirable.
The position requires a highly self-motivated individual, with outstanding organizational skills, the ability to effectively present results and conclusions to co-workers, collaborators and manager. Ability to multitask, work well under pressure and drive personal and team objectives that impact critical timelines is expected. A flexible, collaborative attitude is essential for this position.
Core Competencies
IC – Team with Others:
* Encourage collaboration and input from all team members;
* Value the contributions of all team members; and
* Balance individual and team goals
* Embrace the ideas of others, nurture innovation and manage innovation to reality
IC – Self-Motivation:
* Set high standards of performance;
* Pursue goals with energy and persistence; and
* Drive for results and achievement.
IC – Oral Communication:
* Express ideas clearly and concisely in groups and one-to-one conversations; and
* Create an environment with open channels of communication.
* Analytical, organizational and presentation skills
IC – Leadership skills
* Strong results-driven personality with high level of enthusiasm, energy and confidence.
* Demonstrated excellence and productivity in independent research.
* Create a learning environment, open to suggestions and experimentation for improvement.
EDUCATION: Required: Bachelor's degree in Biology, Biochemistry, Molecular Biology, Cell Biology, Enzymology, Pharmacology, Chemistry or related field.
Preferred: Master's degree in Biology, Biochemistry, Molecular Biology, Cell Biology, Enzymology, Pharmacology, Chemistry or related field.
EXPERIENCE: Required: One year of relevant research experience in lab. With preferred degree, no required experience.
Preferred:
* Master or PhD level degree.
* Practical experience in pipeline engine Snakemake, Nextflow, Cromshell or other equivalent.
* Practical experience in working in HPC, or Cloud like AWS, Azure or GCP.
* Practical experience in data visualization dashboard framework, R/Shiny, Python/Streamlit or R/Dash.
* Practical experience in statistical modeling, machine learning and deep learning using the tools or frameworks,such as TensorFlow, PyTorch, Python/statsmodels, scikit-learn, and other equivalent.
* Experience analyzing ATAC-seq data.
* An understanding of LIMS would be desirable.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
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