Job Abstract

Job Description

The Quantitative Pharmacology and Pharmacometrics (QP2) Department of our Company Research Laboratories in West Point, PA / Rahway, NJ is seeking a curious and collaborative Associate Director to support our rapidly expanding immunology pipeline.

As an Associate Director, you will participate on cross-functional teams of experienced scientists to discover and advance the clinical development of novel therapeutic agents for immunologic disorders.  More specifically, you will apply your quantitative skills with limited supervision to develop and implement translational PK/PD strategies, characterize clinical population pharmacokinetics and pharmacodynamics of biologics, small molecules and non-traditional therapeutics like peptides, novel biological constructs and others, perform clinical trial simulations, comparator modeling and other model-based analyses to inform dose selection and schedule, clinical trial design and go/no-go decisions.  You will apply your expertise to frame critical drug development questions to optimize drug development using model-based approaches and influence cross-functional teams to adopt such strategies. Finally, you maintain a comprehensive understanding of global regulatory expectations and contribute to regulatory documents and interactions with agencies.

The Associate Director is a skilled modeler and a quantitative drug developer, with a strong, integrated understanding of the strategic elements of drug discovery and development and leads the QP2 efforts. The ideal candidate is collaborative, possesses a learning mindset and can work through scientific challenges within and between departments to develop aligned strategies and deliver solutions.  In addition, you share your skills and ideas with the department to advance our science. Excellent communication skills are required including the ability to clearly present scientific data in group settings. 

Within QP2, you have a unique opportunity to accelerate your professional career as a quantitative drug developer taking advantage of our end-to-end pipeline support in one of the world’s most research-intensive biopharmaceutical companies.

Required:

• A Ph.D. or equivalent degree with at least 3 years of experience - OR- a PharmD or equivalent degree with at least 5 years of experience - OR- a MS or equivalent degree with at least 7 years of experience, where “experience” means having a record of increasing responsibility and independence in a similar role in pharmaceutical drug development or academia

• An educational background in PK/PD, pharmaceutical sciences, pharmacometrics, mathematics, statistics/ biostatistics, computational biology/chemistry, or chemical/biomedical engineering.

• Experience in performing population PK / PKPD analyses using standard pharmacometric software (e.g. NONMEM, Monolix, Phoenix, R, Matlab)

• Expertise in development and modeling of complex therapeutic modalities

• Proficiency in written and verbal communication and interdisciplinary collaboration

Preferred:

• An exemplary record of increasing responsibility, independence, and demonstrated impact in driving drug development decisions through application of model-based approaches

• Knowledge of immunologic disorders

• Skills in experimental design, mathematical problem solving, critical data analysis/interpretation, and statistics

• Scientific understanding of ADME and biopharmaceutic properties of biologics, small molecules, or non-traditional therapeutics

• Demonstrated ability to participate in and to lead an interdisciplinary team

Your role at our Company is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders).  Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

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Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here.

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