Job Abstract

Job Description

Position Description:

Associated Principal Scientist

Scientists in the In Vitro Toxicology group within the Investigative Toxicology function of Nonclinical Drug Safety (NDS) contribute to the advancement of our Company's discovery pipeline through the development and application of novel in vitro models/assays to support nonclinical safety testing and de-risking effort.

This specific position is expected to provide scientific leadership and contribute to strategy and execution of various in vitro toxicology projects, provide mentorship and guidance to junior level scientists and lab staff, and drive innovation and new capability development.

The successful candidate should have in depth knowledge and experience of in vitro model/assay development and application pertaining to nonclinical drug safety testing, demonstrated ability to bring and contribute to innovative solutions, work collaboratively across disciplines, and deliver on projects from conception to completion.

Responsibilities:

• Serve as a scientific lead for various in vitro tox and investigative tox projects, contribute to strategy and design, oversee planning and execution to ensure robust delivery of results from beginning to end

• Provide scientific mentorship and guidance to junior scientists and technical staff, assist with troubleshooting

• Collaborate effectively with internal and external partners to drive innovative solutions to nonclinical safety problems and develop new capabilities for investigative toxicology and other nonclinical safety needs

Position Qualifications:

Education Minimum Requirement:

• Doctoral degree in Toxicology, Pharmacology, Bioengineering or a closely related discipline

Required Experience and Skills:

• Minimal 5 years working experience in nonclinical drug safety testing, preferable in a pharmaceutical or biotech industry setting

• Knowledge and experience in the development and application of complex in vitro models and novel in vitro assays for nonclinical safety testing

• Self-motivated, demonstrated ability to lead and deliver on scientific objectives

• Possessing strategic mindset, great problem solving and critical thinking skills

• Good team player and ability to work effectively in a matrixed organization

• Good verbal and written communication

Preferred Experience and Skills:

• Knowledge and experience of drug discovery and development process and the use of NAMs for nonclinical safety testing

• Expertise and experience in applying PKPB modeling to complex in vitro models to enable IVIVC

• Expertise and experience in designing, developing and implementing lab automation, high throughput in vitro assay development, and trouble shooting

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders).  Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

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Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.  This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

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