Job Abstract

Research Associate II, Bioconjugation

Position Summary:

Catalent Pharma Solutions in Emeryville, CA is seeking a Research Associate II who will be responsible for the conjugation, purification, and HPLC (high-performance liquid chromatography) analysis of site-specific antibody-drug conjugates (ADCs).  The Research Associate II reports to the Group Leader, Bioconjugation.

This is a full-time position, Monday – Friday, day shift from 9am-5pm. This position is based in Emeryville, CA, 94608 in the EmeryStation West campus, at 5959 Horton St., easily accessible by BART / EmeryGoRound, AMTRAK, or car (with private, secured, on-site parking provided).

Catalent Pharma Solutions is the leading provider of pharmaceutical development services, drug delivery technologies, manufacturing, packaging, and product commercialization services to the global pharmaceutical and biotechnology industry.  We employ over 18,000 people in more than 50 facilities worldwide with reported annual revenues of approximately $3.998 billion. At Catalent, we take pride in providing a shared commitment to build employee capability, and foster a culture of inclusion, where talent and potential are unleashed, and where employees are committed and engaged to achieve results.

Catalent Biologics Emeryville, CA site, formerly the startup company Redwood Bioscience, has developed a proprietary approach for site-specific bioconjugation to produce next-generation antibody-drug conjugates (ADCs). This technology, termed SMARTag®, is based on use of the aldehyde-tag site-specific protein modification technology and Catalent’s novel conjugation chemistry and proprietary, stable linkers. SMARTag is a clinical-stage technology that was named Runner Up for Best Platform at the 2022 World ADC Awards in San Diego, CA.

The Catalent Biologics Emeryville site comprises a close-knit team of scientists working cross-functionally with each other to nimbly achieve our goals and milestones. We are a research site, working to develop therapeutic ADC drug candidates for clinical testing. We also continuously strive to improve and expand our technology platform. The team has a focus on publishing papers and filing intellectual property to contribute to the exciting and dynamic field of bioconjugation and drug conjugates.

Catalent is committed to a Patient First culture through excellence in quality and compliance, and to the safety of every patient, consumer, and Catalent employee. 

The Role:

• Perform bioconjugation reactions and purify ADCs (Antibody Drug Conjugates) using FPLC (Fast protein liquid chromatography) and diafiltration.
• HPLC/chromatographic analysis of ADCs.
• Maintain an accurate and up to date lab notebook and protein database.
• Proactively communicate results to team.
• Support cross-functional research activities.
• Assist team as needed by performing other related duties, such as formulation or stability studies.
• All other duties as assigned

The Candidate:

•  Bachelor’s degree (B.S.) in Biology, Chemistry or a related discipline required with 1.5+ years of additional research experience in industry. We would also accept a Master’s (M.S.) in Biology, Chemistry, or a related discipline with 0+ years of additional research experience.
• Prior experience with antibody-drug conjugates, including ADC purification and analysis is a plus. Relevant experience in bioconjugation and conjugate purification using FPLC and diafiltration strongly preferred.
• Applicants with experience performing HPLC/chromatographic analysis of conjugates will be favorably considered.
• Candidates should have skills that enable problem solving, data management, effective communication, and collaboration within multidisciplinary teams.
• The ability to establish and meet production goals that consistently meet quality requirements is essential. Must have a desire and ability to learn new skills to help contribute to our multi-disciplinary teams.
• Physical requirements: Individual may be required to sit, stand, walk regularly and occasionally lift up to 10 pounds; ability to communicate orally with customers, vendors, and co-workers. Regular use of telephone and email. Hearing, vision, and speaking within normal ranges is essential for normal conversations, to receive ordinary information and to prepare or inspect documents. Good manual dexterity for the use of common office equipment such as computer terminals, calculator, copiers, and fax machines. Good reasoning ability is important. Able to understand and utilize management reports, memos, and other documents to conduct business.

Pay:

• The anticipated starting salary range for this role in Emeryville, CA is $86,000 to $96,000 annually. The final salary offered to a successful candidate may vary, and will be dependent on several factors that may include but are not limited to: the type and length of experience within the job, type and length of experience within the industry, skillset, education, business needs, etc.  Catalent is a multi-state employer and this salary range may not reflect positions that work in other states.

Why you should join Catalent:

• Awesome team collaboration
• Defined career path and annual performance review and feedback process 
• Diverse, inclusive culture 
• Several Employee Resource Groups focusing on D&I
• 152 hours of PTO + 8 paid holidays
• Dynamic, fast-paced work environment
• Positive working environment focusing on continually improving processes to remain innovative
• Potential for career growth on an expanding team within an organization dedicated to preserving and bettering lives 
• Competitive salary with bonus potential 
• Community engagement and green initiatives 
• Generous 401K match and Paid Time Off accrual 
• Medical, dental and vision benefits effective day one of employment 
• Tuition Reimbursement – Let us help you finish your degree or earn a new one!
• GymPass program to promote overall physical wellness 
• Perkspot - offers exclusive or private discounts from approximately 900+ merchants in a wide array of categories

Catalent offers rewarding opportunities to further your career!  Join the global drug development and delivery leader and help us bring over 7,000 life-saving and life-enhancing products to patients around the world. Catalent is an exciting and growing international company where employees work directly with pharma, biopharma and consumer health companies of all sizes to advance new medicines from early development to clinical trials and to the market. Catalent produces more than 70 billion doses per year, and each one will be used by someone who is counting on us. Join us in making a difference. 

Catalent is committed to the health and safety of its employees, visitors and the customers and patients we serve. As a result of the global pandemic, we have modified many of our recruitment and on-boarding processes to maintain everyone’s safety. The Human Resources teams will communicate all necessary safety processes and procedures throughout each stage.

personal initiative. dynamic pace. meaningful work.

Visit Catalent Careers to explore career opportunities.

Catalent is an Equal Opportunity Employer, including disability and veterans.

If you require reasonable accommodation for any part of the application or hiring process due to a disability, you may submit your request by sending an email, and confirming your request for an accommodation and include the job number, title and location to DisabilityAccommodations@catalent.com. This option is reserved for individuals who require accommodation due to a disability. Information received will be processed by a U.S. Catalent employee and then routed to a local recruiter who will provide assistance to ensure appropriate consideration in the application or hiring process.

Notice to Agency and Search Firm Representatives: Catalent Pharma Solutions (Catalent) is not accepting unsolicited resumes from agencies and/or search firms for this job posting. Resumes submitted to any Catalent employee by a third party agency and/or search firm without a valid written & signed search agreement, will become the sole property of Catalent. No fee will be paid if a candidate is hired for this position as a result of an unsolicited agency or search firm referral. Thank you.

Important Security Notice to U.S. Job Seekers:

Catalent NEVER asks candidates to provide any type of payment, bank details, photocopies of identification, social security number or other highly sensitive personal information during the offer process, and we NEVER do so via email or social media. If you receive any such request, DO NOT respond— it is a fraudulent request. Please forward such requests to spam@catalent.com for us to investigate with local authorities.

California Job Seekers can find our California Job Applicant Notice HERE.