Job Abstract

Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community.

The Shapiro Laboratory at the California Institute of Technology develops bio-molecular technologies for non-invasive imaging and control of cellular function inside living organisms to facilitate basic biology research and the development of cell-based diagnostic and therapeutic agents. We seek an In Vivo Research Manager experienced with small animal research to join our team and help us accomplish this mission. Additional information about the Shapiro group can be found at http://shapirolab.caltech.edu.

The In Vivo Research Manager, reporting directly to Professor Shapiro, will conduct independent and collaborative experiments involving molecular and cellular imaging and control in vivo and support the faculty PI in managing the animal research conducted by the research group. The successful candidate will be an integral member of the research team, alongside postdoctoral fellows and graduate students, and is expected to be a co-author on scientific publications.

• Performs scientific research that includes small animal procedures, such as oral gavage, IV, SC, IP injections, intracranial surgery, and imaging using fluorescence, luminescence, ultrasound, and magnetic resonance.
• May also perform scientific research that includes techniques such as tissue histology, optical microscopy, cell culture, and molecular biology.
• Is expected to be an author on scientific publications.
• Manages animal protocols. Serves as the laboratory’s primary contact with our Institutional Animal Care and Use Committee (IACUC), the Office of Laboratory Animal Resources (OLAR), and Institutional Biosafety Committee (IBC). Leads the development and updating of IACUC protocols in a timely manner. Prepares and maintains IACUC and related biosafety protocols.
• Trains group members on practices related to animal and related biosafety protocols.
• Tracks animal research costs and identifies opportunities to increase efficiency.
• Tracks, maintains, and orders animal research supplies.
• Maintains and purchases equipment related to animal research.
• Interprets and ensures compliance with Institute policies, scientific research protocols, and federal regulations. Serves as a resource on compliance for all research group scientists, students, and staff.
• Works with other groups at Caltech who collaborate with the Shapiro lab to facilitate their in vivo experiments.
• Works with users of the Beckman Institute Center for Deep Tissue Molecular Imaging and Control (DeepMIC) to help them establish methods for in vivo research using the center’s equipment and advises them on relevant IACUC protocols. Provides hands-on assistance with experiments. Coordinates this activity with the director of the DeepMIC center.
• Other duties as assigned.

• Bachelor's or Master’s degree in Biology, Biomedical Engineering or related field.
• Passion for breakthrough research and desire to learn new things.
• 3 or more years’ experience with small animal laboratory research in academia or industry.
• Experience interfacing with IACUC.
• Experience analyzing and interpreting experimental data.
• Excellent interpersonal and problem-solving skills.
• Excellent collaboration and communication skills.
• Ability to exercise discretion and independent decision-making; ability to prioritize work according to urgency; ability to multitask and work under tight deadlines.
• Ability to master new material and adapt to changes in workflow and requirements.
• Lab management experience.

• Resume